NIH-funded research NIH-funded research

Improving care for patients with non-alcoholic fatty liver disease in VA primary care

Official title: Testing the Effectiveness of NAFLD Clinical Care Pathway in VA Primary Care

Funded at Michael E Debakey VA Medical Center · NIH-11018535 · Data updated 2026-11-12

This study is working to help veterans get better care for non-alcoholic fatty liver disease (NAFLD) by using a clear plan that makes it easier for doctors to spot and treat the condition, so they can avoid serious liver problems.

More Primary Care research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionMichael E Debakey VA Medical Center
NIH-funded
Lab location1 site (Houston, United States)
Project startFebruary 1, 2024
Project endJanuary 31, 2028
Funding year2025
NIH project number5I01HX003655-02
Project IDNIH-11018535 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are veterans aged 21 and older who may be at risk for or diagnosed with non-alcoholic fatty liver disease.

Less likely to help

Patients who do not have NAFLD or are not veterans may not receive any benefit from this research.

What this research studies

This research focuses on enhancing the identification and management of non-alcoholic fatty liver disease (NAFLD) among veterans receiving care in primary care settings. It utilizes a structured Clinical Care Pathway that includes a series of steps such as risk identification, targeted history, lab testing, and non-invasive fibrosis assessment. By implementing this pathway, the research aims to ensure that more veterans are accurately diagnosed and receive appropriate treatment for NAFLD, which is crucial for preventing severe liver complications. The study will adapt and test this pathway within the VA system to improve patient outcomes.

Why it matters

Potential benefit: If successful, this research could lead to better diagnosis and management of NAFLD, ultimately reducing the risk of severe liver disease among veterans.

How similar studies have gone: Previous research has shown that structured care pathways can effectively improve patient outcomes in chronic disease management, suggesting a strong potential for success in this approach.

Where this research is happening

  • Michael E Debakey VA Medical Center
    Houston, United States
    Active

Researchers

  • Principal investigator: El-Serag, Hashem B — Michael E Debakey VA Medical Center
  • Study coordinator: El-Serag, Hashem B

Related research

Other NIH-funded projects on the same topics.

  • NAFLD care pathway for Veterans in VA primary care

    This project will introduce a step-by-step screening and follow-up plan in VA primary care to find and manage non-alcoholic fatty liver disease in Veterans.

    NIH research Michael E Debakey VA Medical Center · Houston, United States · NIH-11310734

  • HEARTS hypertension and diabetes care in Guatemala

    This grant tests how well the HEARTS primary care model works in Guatemala to improve blood pressure and blood sugar control for patients.

    NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-11645315

  • Primary Care HEART-NET: boosting access to research in the Deep South

    A collaboration across three universities will build primary care research networks in Alabama, Arkansas, and Mississippi to improve access to care and help prevent and manage chronic diseases.

    NIH research University of Alabama at Birmingham · Birmingham, United States · NIH-11618658

  • Primary Care Bridge: Building Research in Diverse Geographic Settings

    A national network hub in New Mexico will connect rural clinics and communities to faster, more usable primary care research so patients in underserved areas can benefit from new evidence.

    NIH research University of New Mexico Health Scis Ctr · Albuquerque, United States · NIH-11618652

  • WREN: Expanding Research Capacity in Rural Primary Care Clinics

    A nationwide network in Wisconsin will strengthen rural primary care clinics to participate in real-world research and bring more clinical trials to communities.

    NIH research University of Wisconsin-Madison · Madison, United States · NIH-11618649

  • Primary care research network in Oklahoma to boost rural patient trials

    A nationwide NIH-supported effort to strengthen Oklahoma’s primary care research network so doctors can run big clinical trials and real‑world studies in rural communities.

    NIH research University of Oklahoma Hlth Sciences Ctr · Oklahoma City, United States · NIH-11618645

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.