Improving care for patients with drug-resistant epilepsy
Official title: Optimizing Care for Patients with Drug-Resistant Epilepsy
Funded at University of Michigan at Ann Arbor · NIH-11067774 · Data updated 2026-11-12
This study is all about creating a helpful mobile app that makes it easier for people with drug-resistant epilepsy to share what matters most to them with their doctors, like their mental health and daily life, so they can work together to improve their overall care.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project start | December 15, 2022 |
| Project end | November 30, 2027 |
| Funding year | 2025 |
| Award (this year) | $220,271 |
| NIH project number | 5K23NS126495-03 |
| Project ID | NIH-11067774 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with drug-resistant epilepsy who are seeking better management of their condition.
✕Less likely to help
Patients who have well-controlled epilepsy or those who do not have access to mobile health technology may not benefit from this research.
What this research studies
This research focuses on enhancing communication between patients with drug-resistant epilepsy and their healthcare providers. It aims to develop a mobile health tool that helps patients express their care priorities, which may include factors beyond just seizure control, such as mental health and cognitive function. By aligning treatment goals with patient priorities, the research seeks to improve overall patient-centered outcomes. The approach involves designing and testing this communication tool to ensure it meets the needs of patients effectively.
Why it matters
Potential benefit: If successful, this research could lead to improved quality of life and better clinical outcomes for patients with drug-resistant epilepsy.
How similar studies have gone: Previous research has shown that communication tools can significantly enhance patient-centered outcomes in other clinical areas, suggesting potential success for this novel approach.
Where this research is happening
-
University of Michigan at Ann Arbor
Ann Arbor, United States Active
Researchers
- Principal investigator: Hill, Chloe E — University of Michigan at Ann Arbor
- Study coordinator: Hill, Chloe E
Related research
Other NIH-funded projects on the same topics.
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Single-pulse brain stimulation to improve epilepsy surgery outcomes
A new approach uses single-pulse electrical stimulation to better locate seizure-causing brain regions before epilepsy surgery, with the goal of improving chances of seizure freedom.
-
New MRI markers to find seizure zones in hard-to-treat epilepsy
Aims to use advanced MRI measures of brain stiffness and blood flow to better locate seizure regions in people with drug-resistant epilepsy.
-
Mapping hidden brain cell changes in drug-resistant epilepsy
This project looks for tiny genetic changes in brain cells of children with drug-resistant epilepsy caused by brain malformations to help guide better diagnosis and treatments.
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Finding seizure-causing brain regions in drug-resistant epilepsy using computer models
This project uses computer models of brain activity to help doctors find the areas that start seizures in people whose epilepsy does not respond to medicines.
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Noninvasive brain mapping to find seizure networks in children with hard-to-treat epilepsy
This project uses noninvasive brain recordings and connectivity maps to help locate seizure-causing networks in children whose epilepsy does not respond to medication.
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Closed-loop implant to target seizure-related high-frequency brain waves in drug-resistant epilepsy
An implantable device will try to find and interrupt seizure-related high-frequency brain waves in people whose seizures don't respond to medicines.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.