Improving care for patients with alcohol-related liver disease undergoing liver transplantation
Official title: 3/4-The INTEGRATE Study: Evaluating INTEGRATEd Care to Improve Biopsychosocial Outcomes of Early Liver Transplantation for Alcohol-Associated Liver Disease
Funded at University of Miami School of Medicine · NIH-10904906 · Data updated 2026-11-12
This study is looking at how better teamwork among doctors and healthcare providers can help people with alcohol-related liver disease who are getting a liver transplant, by understanding what influences their chances of getting referred for the transplant and how different personal and social factors can affect their recovery.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Miami School of Medicine NIH-funded |
| Lab location | 1 site (Coral Gables, United States) |
| Project start | August 10, 2023 |
| Project end | July 31, 2030 |
| Funding year | 2024 |
| Award (this year) | $399,037 |
| NIH project number | 5R01AA030968-02 |
| Project ID | NIH-10904906 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with alcohol-associated liver disease who are being considered for early liver transplantation.
✕Less likely to help
Patients with liver disease not associated with alcohol or those who have already undergone liver transplantation may not benefit from this research.
What this research studies
This research investigates how integrated care can enhance the outcomes for patients with alcohol-associated liver disease who are undergoing early liver transplantation. It aims to identify the factors that influence referrals for transplantation and develop models to predict patient outcomes based on biopsychosocial factors. The study will involve collaboration among diverse healthcare professionals to ensure comprehensive care and support for patients. By focusing on both medical and social aspects, the research seeks to improve the overall success of liver transplants in this population.
Why it matters
Potential benefit: If successful, this research could lead to better health outcomes and increased survival rates for patients with alcohol-related liver disease receiving liver transplants.
How similar studies have gone: Previous studies have shown promising results in integrated care approaches for similar conditions, suggesting potential for success in this research.
Where this research is happening
-
University of Miami School of Medicine
Coral Gables, United States Active
Researchers
- Principal investigator: Goldberg, David Seth — University of Miami School of Medicine
- Study coordinator: Goldberg, David Seth
Related research
Other NIH-funded projects on the same topics.
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-
Regulatory dendritic cell therapy to reduce immunosuppressive drugs after liver transplant
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-
HOPE liver transplant: reducing infections and cancer risk for HIV-positive recipients
This grant aims to better understand why HIV-positive liver transplant recipients face higher infection and cancer risks and to improve safety and outcomes for these patients.
-
Early liver transplant decisions for severe alcohol-related liver disease
A large study follows adults with severe alcohol-related liver disease to understand how to best select and manage patients for early liver transplantation.
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Early Liver Transplant for Severe Alcoholic Hepatitis
A hospital-based program is studying whether offering an early liver transplant to patients with severe alcoholic hepatitis can save lives when standard medical treatment fails.
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Early liver transplant for severe alcoholic hepatitis (SAH) to save lives
A Johns Hopkins program is testing whether giving an early liver transplant to patients with severe alcoholic hepatitis who can’t be helped by standard treatments can save lives and reduce relapse risk.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.