Improving care for leukemia and other blood cancers
Official title: Project 03: Leukemia and Hematological Malignancies Research (LHM)
Funded at Ohio State University · NIH-11263185 · Data updated 2026-11-12
This program is developing better ways to diagnose, predict outcomes, and treat leukemia and related blood cancers for children and adults.
Quick facts
| Grant type | P30 center grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ohio State University NIH-funded |
| Lab location | 1 site (Columbus, UNITED STATES) |
| Project start | September 12, 1997 |
| Project end | March 31, 2031 |
| Funding year | 2026 |
| Award (this year) | $58,203 |
| NIH project number | 2P30CA016058-50 |
| Project ID | NIH-11263185 on NIH RePORTER |
Who could benefit from this research
✓Could help
People of any age with leukemia or related blood disorders (for example AML, CLL, MDS, MPNs, or multiple myeloma) who can travel to or enroll at the Ohio State Cancer Center or partner sites may be eligible.
✕Less likely to help
People with cancers not related to blood or those unable to travel to the study sites are unlikely to be eligible or directly benefit from this program.
What this research studies
At The Ohio State University Comprehensive Cancer Center, a multidisciplinary team of physicians, scientists, and engineers studies the causes and behavior of leukemia and other blood cancers. They combine lab experiments, genetic and other 'omics' testing, immune-system analyses, and patient information to find new treatment targets and improve risk prediction. The program supports preclinical work, clinical trials, and studies that collect patient samples and data across the lifespan from pediatric to geriatric patients. Findings are translated into clinical trials and treatment strategies that people with blood cancers could potentially join.
Why it matters
Potential benefit: If successful, this work could produce more accurate risk predictions and new, more personalized treatments and clinical trials for people with blood cancers.
How similar studies have gone: Other large leukemia research programs have led to successful targeted therapies and better risk tools, though many approaches tested here are still being refined.
Where this research is happening
-
Ohio State University
Columbus, United States Active
Researchers
- Principal investigator: Woyach, Jennifer a. — Ohio State University
- Study coordinator: Woyach, Jennifer a.
Related research
Other NIH-funded projects on the same topics.
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Investigating a specific type of leukemia in children caused by genetic changes.
This study is looking at how certain proteins linked to leukemia affect kids and teens with high-risk blood cancers, and the researchers hope to find new ways to treat these conditions by learning more about how the disease works.
-
Caregiver-led mobile tool to support healthy habits for kids treated for ALL
A caregiver-directed mobile program helps children who were treated for acute lymphoblastic leukemia build healthier daily routines.
-
Targeting the SCP4 pathway in acute myeloid leukemia (AML)
Aims to uncover how the SCP4 signaling pathway drives AML and how it could be blocked to help patients.
-
Understanding TCRs in Leukemia to Improve Immunotherapies
A short, patient-friendly look at a project trying to map how immune cells recognize leukemia so future therapies can be better and safer for people with AML.
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Targeted therapy for AML using DHODH inhibitors to boost differentiation and immune response
Aims to help adults with acute myeloid leukemia by using a special drug approach that makes cancer cells act more like normal blood cells and supports the immune system.
-
Genomics of childhood ALL across global populations
A wide-ranging study looks at how inherited genetics influence the risk of childhood acute lymphoblastic leukemia around the world.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.