Improving care for heart injury during sepsis
Informing best practices for evaluation and treatment of myocardial injury during sepsis
['FUNDING_R01'] · UNIV OF MASSACHUSETTS MED SCH WORCESTER · NIH-11143629
This project aims to find better ways to understand and treat heart muscle injury that can happen when someone has sepsis.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIV OF MASSACHUSETTS MED SCH WORCESTER (nih funded) |
| Locations | 1 site (WORCESTER, UNITED STATES) |
| Trial ID | NIH-11143629 on ClinicalTrials.gov |
What this research studies
Sepsis is a serious infection that can lead to organ problems, and about half of those affected also experience heart muscle injury. Currently, there isn't much clear guidance on how best to care for these patients. This project will look at existing patient health records from two large healthcare systems. By examining these records, we hope to learn how heart injury in sepsis is currently managed and identify which treatments, especially blood thinners, work best for different patients. This information will help doctors make more informed decisions about care.
Who could benefit from this research
Good fit: Patients who have experienced heart muscle injury as a complication of sepsis are the focus of this research.
Not a fit: Patients who have not had sepsis or heart muscle injury related to sepsis would not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this work could lead to clearer guidelines for doctors, helping them choose the most effective treatments for patients experiencing heart injury during sepsis.
How similar studies have performed: While the overall approach of using electronic health records for outcomes research is established, specific guidance for myocardial injury in sepsis remains limited, making this a novel contribution.
Where this research is happening
WORCESTER, UNITED STATES
- UNIV OF MASSACHUSETTS MED SCH WORCESTER — WORCESTER, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: WALKEY, ALLAN J. — UNIV OF MASSACHUSETTS MED SCH WORCESTER
- Study coordinator: WALKEY, ALLAN J.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.