Improving Care for Critically Ill Children
Official title: Collaborative Pediatric Critical Care Research Network - Clinical Site
Funded at Research Inst Nationwide Children's Hosp · NIH-11182715 · Data updated 2026-11-12
This project brings together hospitals to find better ways to care for very sick children, especially those with severe infections like sepsis.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Research Inst Nationwide Children's Hosp NIH-funded |
| Lab location | 1 site (Columbus, United States) |
| Project start | August 18, 2021 |
| Project end | July 31, 2026 |
| Funding year | 2025 |
| Award (this year) | $154,000 |
| NIH project number | 5RL1HD107783-05 |
| Project ID | NIH-11182715 on NIH RePORTER |
Who could benefit from this research
✓Could help
This research is designed for critically ill children, particularly those aged 0-11 years old who are admitted to the intensive care unit with severe conditions like sepsis.
✕Less likely to help
Children who are not critically ill or do not have conditions being specifically addressed by the network's current studies may not directly benefit from this particular research.
What this research studies
Our hospital is part of a special group of children's hospitals working together to improve care for critically ill children. We are focused on understanding and treating severe conditions like sepsis, a life-threatening infection. This involves conducting carefully designed studies, including those that test new medicines to help children's immune systems fight off illness. Our goal is to find personalized treatments that can make a real difference for children in intensive care.
Why it matters
Potential benefit: If successful, this work could lead to more effective and personalized treatments for critically ill children, improving their chances of recovery.
How similar studies have gone: Previous work by this network has successfully established the safety and feasibility of monitoring and adjusting immune function in critically ill children, paving the way for these new studies.
Where this research is happening
-
Research Inst Nationwide Children's Hosp
Columbus, United States Active
Researchers
- Principal investigator: Hall, Mark W — Research Inst Nationwide Children's Hosp
- Study coordinator: Hall, Mark W
Related research
Other NIH-funded projects on the same topics.
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Collaborative Pediatric Critical Care Clinical Site (CPCCRN)
A nationwide network is testing personalized care approaches for seriously ill children with sepsis to improve outcomes.
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Collaborative Pediatric Critical Care Research Network: personalized care for septic kids
A nationwide network is testing personalized treatment approaches for children with sepsis-related organ failure to improve outcomes.
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Collaborative Pediatric Critical Care Network Site: Kids’ Sepsis Care
A pediatric-focused NIH grant supports a network site that helps tailor sepsis care for critically ill children across multiple centers.
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Personalized care for septic children through immunomodulation in MODS
This project tests a custom approach to treating pediatric sepsis in kids with organ failure by tailoring treatments to each child’s immune profile.
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Personalized immune-based care for septic kids with organ failure
A network study helps critically ill children with sepsis who have organ failure by tailoring treatments to their individual immune profiles.
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Collaborative Pediatric Critical Care Clinical Site for Precision Sepsis Care
A pediatric-focused research grant exploring personalized care for kids with severe sepsis to improve outcomes.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.