Improving care for children with severe infections and organ problems
Official title: Collaborative Pediatric Critical Care Research Network - Clinical Site
Funded at Baylor College of Medicine · NIH-11176722 · Data updated 2026-11-12
This project aims to find better ways to treat children who get very sick from infections, leading to organ problems.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Baylor College of Medicine NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project start | August 18, 2021 |
| Project end | July 31, 2026 |
| Funding year | 2025 |
| Award (this year) | $160,500 |
| NIH project number | 5RL1HD107780-05 |
| Project ID | NIH-11176722 on NIH RePORTER |
Who could benefit from this research
✓Could help
Children who are critically ill with severe infections causing multiple organ dysfunction may be candidates for future participation in related clinical trials.
✕Less likely to help
Patients who are adults or children not experiencing severe infections with multiple organ dysfunction would not directly benefit from this specific research.
What this research studies
We are expanding a network of children's hospitals across the country to work together on important health challenges. One key effort is a new clinical trial focused on personalized treatments for children with severe infections that cause multiple organs to struggle. This trial will explore how to adjust treatments based on each child's unique immune response. Our goal is to improve how we care for these critically ill children.
Why it matters
Potential benefit: If successful, this work could lead to more effective, personalized treatments for children suffering from severe infections and organ failure, potentially saving lives and improving recovery.
How similar studies have gone: This project builds upon an extensive track record of successful collaboration in multi-center clinical trials, suggesting a strong foundation for its approach.
Where this research is happening
-
Baylor College of Medicine
Houston, United States Active
Researchers
- Principal investigator: Akcan Arikan, Ayse — Baylor College of Medicine
- Study coordinator: Akcan Arikan, Ayse
Related research
Other NIH-funded projects on the same topics.
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Collaborative Pediatric Critical Care Clinical Site (CPCCRN)
A nationwide network is testing personalized care approaches for seriously ill children with sepsis to improve outcomes.
-
Collaborative Pediatric Critical Care Research Network: personalized care for septic kids
A nationwide network is testing personalized treatment approaches for children with sepsis-related organ failure to improve outcomes.
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Collaborative Pediatric Critical Care Network Site: Kids’ Sepsis Care
A pediatric-focused NIH grant supports a network site that helps tailor sepsis care for critically ill children across multiple centers.
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Personalized care for septic children through immunomodulation in MODS
This project tests a custom approach to treating pediatric sepsis in kids with organ failure by tailoring treatments to each child’s immune profile.
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Personalized immune-based care for septic kids with organ failure
A network study helps critically ill children with sepsis who have organ failure by tailoring treatments to their individual immune profiles.
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Collaborative Pediatric Critical Care Clinical Site for Precision Sepsis Care
A pediatric-focused research grant exploring personalized care for kids with severe sepsis to improve outcomes.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.