Improving cardiac imaging with advanced motion correction technologies
Official title: Development and Translation of Advanced Motion Correction Technologies for Cardiac PET/CT
Funded at Yale University · NIH-11076288 · Data updated 2026-11-12
This study is working on improving heart scans using a special imaging technique called PET, making them clearer and more accurate by reducing the blurriness caused by movement, like breathing or heartbeats, so that doctors can better understand your heart health without needing extra equipment.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project start | April 17, 2024 |
| Project end | March 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $686,047 |
| NIH project number | 5R01HL169868-02 |
| Project ID | NIH-11076288 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients undergoing cardiac PET imaging, particularly those with conditions like coronary artery disease or aortic stenosis.
✕Less likely to help
Patients who are not undergoing cardiac imaging or those with stable heart conditions that do not require advanced imaging techniques may not benefit from this research.
What this research studies
This research focuses on enhancing the quality of cardiac PET imaging by developing advanced motion correction technologies. It aims to address issues caused by various types of motion, such as respiratory and cardiac motion, which can degrade image quality and accuracy. The approach involves creating data-driven methods that do not require external tracking hardware, making it more accessible for clinical use. The research specifically targets the use of 82Rb as a tracer, which presents unique challenges due to its rapid kinetics and short half-life.
Why it matters
Potential benefit: If successful, this research could lead to clearer and more accurate cardiac imaging, improving diagnosis and treatment planning for patients with heart conditions.
How similar studies have gone: Previous research has shown promise in motion correction technologies for imaging, suggesting that this approach could lead to significant advancements in cardiac imaging.
Where this research is happening
-
Yale University
New Haven, United States Active
Researchers
- Principal investigator: Liu, Chi — Yale University
- Study coordinator: Liu, Chi
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.