Improving cancer treatment with radiation therapy
Official title: Core C: Radiosensitization Core
Funded at University of Michigan at Ann Arbor · NIH-10917041 · Data updated 2026-11-12
This study is looking at ways to make radiation therapy work better for cancer patients by testing different treatments that can help tumors respond more effectively to the radiation.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project start | August 14, 2023 |
| Project end | July 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $114,186 |
| NIH project number | 5P50CA269022-02 |
| Project ID | NIH-10917041 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients with specific types of cancer who are undergoing or considering radiation therapy as part of their treatment plan.
✕Less likely to help
Patients with non-cancerous conditions or those not receiving radiation therapy may not benefit from this research.
What this research studies
This research focuses on enhancing the effectiveness of radiation therapy for cancer by evaluating how different therapeutic agents can sensitize tumors to radiation. The team will use advanced techniques to irradiate cultured cells and animal models, developing precise treatment plans for targeting tumors. By utilizing imaging technologies, they aim to optimize the combination of therapies to improve patient outcomes. The project also involves collaboration with various resources at the Rogel Cancer Center to ensure comprehensive support for the research activities.
Why it matters
Potential benefit: If successful, this research could lead to more effective cancer treatments that improve survival rates and reduce side effects for patients undergoing radiation therapy.
How similar studies have gone: Previous research has shown promising results in enhancing radiation therapy effectiveness through sensitization strategies, indicating a strong potential for success in this approach.
Where this research is happening
-
University of Michigan at Ann Arbor
Ann Arbor, United States Active
Researchers
- Principal investigator: Rehemtulla, Alnawaz — University of Michigan at Ann Arbor
- Study coordinator: Rehemtulla, Alnawaz
Related research
Other NIH-funded projects on the same topics.
-
Expanding genetic testing for cancer risk in patients and families
This study is working to make it easier for cancer patients in Michigan to get genetic testing for cancer risk by improving how doctors gather family history and assess genetic risks, so that more people can receive the important evaluations they need.
-
HEARTS hypertension and diabetes care in Guatemala
This grant tests how well the HEARTS primary care model works in Guatemala to improve blood pressure and blood sugar control for patients.
-
Why the retina can sometimes heal itself and how we might help it heal
This NIH grant explores how inflammation and neural cells interact in the zebrafish retina to understand retinal neuron death and regeneration, with potential implications for human vision.
-
Integrated Heart Health: A HEARTS-based approach to hypertension and diabetes in Guatemala
A study tests a team-based, stepwise care model to improve blood pressure and blood sugar control for people with both hypertension and diabetes in Guatemala.
-
Understanding how work exposures and genes influence ALS risk
A study is building a long-term group of people at higher risk for ALS to see how their jobs, exposures at work, and genes together affect if and when the disease might develop.
-
An integrated mobile health program to reduce SAVA and mental health problems among female sex workers in Kenya
A new mobile health program aims to help female sex workers in Kenya avoid substance abuse, violence, HIV, and depression by delivering group therapy, online resources, and a peer discussion space.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.