Improving cancer treatment with advanced MRI technology for better radiation therapy

Toward precision radiotherapy: Physiological modeling of respiratory motion based on ultra-quality 4D-MRI

NIH-funded research University of Virginia · NIH-10653082

This study is working on new imaging techniques to help doctors see tumors more clearly while they move during breathing, so they can give radiation treatment more accurately and safely, which could lead to better outcomes for cancer patients.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Virginia NIH-funded
Lab location1 site (Charlottesville, United States)
Project IDNIH-10653082 on NIH RePORTER

What this research studies

This research focuses on enhancing precision in radiotherapy by developing advanced imaging techniques that account for respiratory motion during treatment. It aims to create ultra-quality four-dimensional MRI images that provide better visualization of tumors and their movement, which is crucial for accurately targeting radiation. By improving the accuracy of image guidance and motion management, the project seeks to ensure that radiation is delivered more precisely to cancerous tissues while minimizing exposure to surrounding healthy tissues. Patients may benefit from more effective and safer radiation treatments as a result of this innovative approach.

Who could benefit from this research

Good fit: Ideal candidates for this research are patients undergoing radiotherapy for abdominal or thoracic cancers who experience respiratory motion during treatment.

Not a fit: Patients with non-respiratory related cancers or those not receiving radiotherapy may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective and safer radiation therapy for cancer patients.

How similar studies have performed: Previous research has shown promise in using advanced imaging techniques for improving radiotherapy, indicating that this approach has the potential for success.

Where this research is happening

Charlottesville, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Cancersneoplasm/cancer
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.