Improving cancer treatment planning using detailed ionization data
Ionization Detail - Biologically based treatment planning for particle therapy beyond LET-RBE
['FUNDING_R01'] · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · NIH-10914878
This study is working on a new way to improve cancer treatment plans for patients receiving proton and carbon ion therapies by using detailed information about how radiation interacts with cells, so that doctors can create more accurate and effective treatments.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA, SAN FRANCISCO (nih funded) |
| Locations | 1 site (SAN FRANCISCO, UNITED STATES) |
| Trial ID | NIH-10914878 on ClinicalTrials.gov |
What this research studies
This research focuses on enhancing treatment planning for cancer therapies that use charged particles, such as protons and carbon ions. It aims to develop a new method that utilizes detailed ionization events at the nanometer scale to better predict the biological effects of radiation, compared to traditional models. By integrating this new approach into clinical practice, the research seeks to provide more accurate and effective treatment plans for patients undergoing particle therapy. The methodology involves comparing existing models and refining them based on the new ionization detail data.
Who could benefit from this research
Good fit: Ideal candidates for this research are cancer patients who are being considered for proton or carbon ion therapy.
Not a fit: Patients who are not undergoing particle therapy or those with conditions not treated by this method may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized cancer treatments, improving patient outcomes.
How similar studies have performed: Previous research has shown promise in using detailed ionization data to improve treatment planning, indicating that this approach could be a significant advancement in the field.
Where this research is happening
SAN FRANCISCO, UNITED STATES
- UNIVERSITY OF CALIFORNIA, SAN FRANCISCO — SAN FRANCISCO, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: FADDEGON, BRUCE — UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
- Study coordinator: FADDEGON, BRUCE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.