Improving cancer treatment for children with HIV in sub-Saharan Africa

Pediatric HIV/AIDS & Infection-Related Malignancies Research Consortium for sub-Saharan Africa (PARCA)

NIH-funded research Baylor College of Medicine · NIH-10895416

This study is working to improve treatment and survival for children with HIV-related cancers in sub-Saharan Africa by using better medical practices and teamwork in countries like Uganda, Malawi, and Botswana, so that these kids have a better chance of getting well.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionBaylor College of Medicine NIH-funded
Lab location1 site (Houston, United States)
Project IDNIH-10895416 on NIH RePORTER

What this research studies

This research aims to establish a collaborative framework to enhance the treatment and outcomes for children with HIV-associated cancers in sub-Saharan Africa. By leveraging existing clinical infrastructures in countries like Uganda, Malawi, and Botswana, the project seeks to implement state-of-the-art treatments and innovative research methodologies. The initiative will focus on addressing the significant disparity in survival rates between children with cancer in the U.S. and those in sub-Saharan Africa, where over 80% currently do not survive. Through collaboration and shared resources, the goal is to improve care and increase survival rates for these vulnerable children.

Who could benefit from this research

Good fit: Ideal candidates for this research are children aged 0-11 years old diagnosed with HIV and associated malignancies living in sub-Saharan Africa.

Not a fit: Patients outside the age range of 0-11 years or those without HIV-related malignancies may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly improve survival rates and quality of life for children with HIV-related malignancies in sub-Saharan Africa.

How similar studies have performed: Previous research has shown success in improving pediatric cancer outcomes through collaborative frameworks in other regions, suggesting a promising potential for this approach in sub-Saharan Africa.

Where this research is happening

Houston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions AIDS associated cancerAIDS related cancerAcquired Immune Deficiency SyndromeAcquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.