Improving Cancer Surgery with Special Imaging
Advancing molecular fluorescence-guided surgery platform
This work helps surgeons see cancer more clearly during operations using special dyes and imaging tools.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Dartmouth College NIH-funded |
| Lab location | 1 site (Hanover, United States) |
| Project ID | NIH-11073051 on NIH RePORTER |
What this research studies
This project focuses on making surgery for cancers like glioma and head and neck cancers more effective. We are developing and testing new fluorescent dyes that can highlight tumor cells, allowing surgeons to distinguish them from healthy tissue. By using these dyes and advanced imaging equipment, doctors hope to remove more of the cancer while preserving healthy areas. This approach aims to improve surgical outcomes and potentially reduce the need for follow-up treatments.
Who could benefit from this research
Good fit: Patients with certain cancers, such as glioma and head and neck cancers, who are undergoing surgery might be ideal candidates for future applications of this technology.
Not a fit: Patients whose cancers are not suitable for this type of imaging or who are not undergoing surgical removal of their tumor may not directly benefit from this specific approach.
Why it matters
Potential benefit: If successful, this could lead to more complete removal of cancer during surgery, potentially improving patient outcomes and reducing recurrence.
How similar studies have performed: This project builds upon previous success in bringing a fluorescent agent from animal models to early-stage human clinical trials.
Where this research is happening
Hanover, United States
- Dartmouth College — Hanover, United States (Active)
Researchers
- Principal investigator: Paulsen, Keith D. — Dartmouth College
- Study coordinator: Paulsen, Keith D.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.