Improving cancer screening for Veterans with inflammatory bowel disease

Mathematical Optimization of Surveillance Ages to Intercept colitis-associated Colorectal cancer (MOSAIC)

['FUNDING_OTHER'] · VA SAN DIEGO HEALTHCARE SYSTEM · NIH-10852818

This study is looking to improve how we check for colorectal cancer in Veterans with inflammatory bowel disease (IBD) by finding out the best times for screenings based on individual risk, so that everyone gets the right care without unnecessary tests.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorVA SAN DIEGO HEALTHCARE SYSTEM (nih funded)
Locations1 site (SAN DIEGO, UNITED STATES)
Trial IDNIH-10852818 on ClinicalTrials.gov

What this research studies

This research aims to enhance the screening and surveillance methods for Veterans suffering from inflammatory bowel disease (IBD), who are at a higher risk of developing colorectal cancer. Currently, the VA uses a standard approach for over 90,000 patients, which may not be suitable for everyone due to the varying levels of individual risk. The project will investigate genetic factors and cellular changes to determine the best times for screening, potentially reducing unnecessary procedures. By utilizing advanced computational tools, the research seeks to create more personalized and effective screening strategies.

Who could benefit from this research

Good fit: Ideal candidates for this research are Veterans diagnosed with inflammatory bowel disease who are at increased risk for colorectal cancer.

Not a fit: Patients without inflammatory bowel disease or those not at risk for colorectal cancer may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more tailored and effective cancer screening protocols, reducing unnecessary procedures and improving early detection for Veterans at risk.

How similar studies have performed: Previous research has shown promise in personalized screening approaches for cancer, indicating potential success for this novel methodology.

Where this research is happening

SAN DIEGO, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Barrett Syndrome

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.