Improving cancer detection in head and neck cancer patients using advanced imaging techniques.
Secondary Molecular Imaging (SMI) for head and neck cancer
This study is testing a new imaging method that uses a special antibody to help doctors get a clearer picture of head and neck cancer, aiming to reduce false alarms and unnecessary procedures for patients who might be worried about their results.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Vanderbilt University Medical Center NIH-funded |
| Lab location | 1 site (Nashville, United States) |
| Project ID | NIH-11021018 on NIH RePORTER |
What this research studies
This research investigates a new imaging method using a radiolabeled anti-EGFR antibody to improve the detection of head and neck squamous cell carcinoma (HNSCC). Current imaging techniques can lead to many false positives, causing unnecessary anxiety and procedures for patients. By using this advanced imaging approach, the study aims to provide more accurate results, particularly for patients with indeterminate findings from standard imaging. The goal is to reduce the need for invasive biopsies and improve the overall diagnostic process for patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients with advanced stage head and neck squamous cell carcinoma who have indeterminate findings on standard imaging.
Not a fit: Patients with early-stage head and neck cancer or those without indeterminate imaging results may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate cancer detection, reducing unnecessary procedures and anxiety for patients.
How similar studies have performed: Other research has shown promise in using targeted imaging techniques for cancer detection, suggesting potential success for this novel approach.
Where this research is happening
Nashville, United States
- Vanderbilt University Medical Center — Nashville, United States (Active)
Researchers
- Principal investigator: Rosenthal, Eben L. — Vanderbilt University Medical Center
- Study coordinator: Rosenthal, Eben L.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.