NIH-funded research R01 grant

Improving cancer care by addressing depression, pain, and fatigue

Official title: Hybrid Type I Cluster Randomized Effectiveness-Implementation Trial of CARES

Funded at University of Pittsburgh at Pittsburgh · NIH-11024393 · Data updated 2026-11-12

This study is looking at a new way to help cancer patients feel better by using a team approach to tackle issues like depression, pain, and fatigue, making sure they get the right care when they need it.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Pittsburgh at Pittsburgh
NIH-funded
Lab location1 site (Pittsburgh, United States)
Project startDecember 15, 2024
Project endNovember 30, 2029
Funding year2025
Award (this year)$669,324
NIH project number1R01CA296402-01
Project IDNIH-11024393 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are cancer patients experiencing clinically significant levels of depression, pain, or fatigue.

Less likely to help

Patients who are not currently undergoing treatment for cancer or do not experience the targeted symptoms may not benefit from this research.

What this research studies

This research investigates a new approach to improve the quality of life for cancer patients by implementing a collaborative care model that addresses common symptoms such as depression, pain, and fatigue. The CARES intervention integrates electronic health record (EHR) screening with a stepped care approach to ensure patients receive timely treatment for these distressing symptoms. By focusing on enhancing treatment initiation and reducing barriers to care, the study aims to improve overall health outcomes and reduce healthcare costs for cancer patients.

Why it matters

Potential benefit: If successful, this research could significantly enhance the quality of life for cancer patients by ensuring they receive effective treatment for their symptoms.

How similar studies have gone: Previous studies have shown success with similar collaborative care approaches in improving patient outcomes in cancer care.

Where this research is happening

  • University of Pittsburgh at Pittsburgh
    Pittsburgh, United States
    Active

Researchers

  • Principal investigator: Steel, Jennifer L. — University of Pittsburgh at Pittsburgh
  • Study coordinator: Steel, Jennifer L.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.