Improving cancer care by addressing depression, pain, and fatigue

Hybrid Type I Cluster Randomized Effectiveness-Implementation Trial of CARES

['FUNDING_R01'] · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · NIH-11024393

This study is looking at a new way to help cancer patients feel better by using a team approach to tackle issues like depression, pain, and fatigue, making sure they get the right care when they need it.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF PITTSBURGH AT PITTSBURGH (nih funded)
Locations1 site (PITTSBURGH, UNITED STATES)
Trial IDNIH-11024393 on ClinicalTrials.gov

What this research studies

This research investigates a new approach to improve the quality of life for cancer patients by implementing a collaborative care model that addresses common symptoms such as depression, pain, and fatigue. The CARES intervention integrates electronic health record (EHR) screening with a stepped care approach to ensure patients receive timely treatment for these distressing symptoms. By focusing on enhancing treatment initiation and reducing barriers to care, the study aims to improve overall health outcomes and reduce healthcare costs for cancer patients.

Who could benefit from this research

Good fit: Ideal candidates for this research are cancer patients experiencing clinically significant levels of depression, pain, or fatigue.

Not a fit: Patients who are not currently undergoing treatment for cancer or do not experience the targeted symptoms may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly enhance the quality of life for cancer patients by ensuring they receive effective treatment for their symptoms.

How similar studies have performed: Previous studies have shown success with similar collaborative care approaches in improving patient outcomes in cancer care.

Where this research is happening

PITTSBURGH, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Cancer Center, Cancers

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.