NIH-funded research NIH-funded research

Improving buprenorphine treatment for opioid use disorder in emergency departments

Official title: A multi-team system implementation strategy to improve buprenorphine adherence for patients who initiate treatment in the emergency department

Funded at University of California at Davis · NIH-10740793 · Data updated 2026-11-12

This study is looking to make buprenorphine treatment more effective for people with opioid use disorder by creating a supportive team approach that connects emergency department staff with primary care providers, so patients get the ongoing help they need to stick with their treatment and feel better over time.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of California at Davis
NIH-funded
Lab location1 site (Davis, United States)
Project startAugust 1, 2023
Project endJuly 31, 2025
Funding year2023
Award (this year)$1,005,183
NIH project number1R61DA059027-01
Project IDNIH-10740793 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals who have initiated buprenorphine treatment for opioid use disorder in emergency departments.

Less likely to help

Patients who are not seeking treatment for opioid use disorder or those who have not initiated buprenorphine in an emergency department may not benefit from this research.

What this research studies

This research aims to enhance the effectiveness of buprenorphine treatment for patients with opioid use disorder (OUD) who begin their treatment in emergency departments. It focuses on developing a coordinated care strategy that fosters ongoing partnerships between emergency department staff and primary care teams, rather than relying on one-time referrals. By implementing a multi-team system approach, the study seeks to improve patient adherence to buprenorphine treatment and ensure better long-term outcomes. Patients will be monitored and supported throughout their treatment journey to address barriers to care and improve retention rates.

Why it matters

Potential benefit: If successful, this research could significantly reduce opioid overdose deaths by improving access to and adherence to buprenorphine treatment for patients with OUD.

How similar studies have gone: Previous research has shown that emergency department-initiated buprenorphine can increase treatment rates, but this approach to improving care coordination is novel and has not been extensively tested.

Where this research is happening

  • University of California at Davis
    Davis, United States
    Active

Researchers

  • Principal investigator: Henry, Stephen G — University of California at Davis
  • Study coordinator: Henry, Stephen G

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.