Improving Breast Cancer Treatment with Imaging

Project 2: Non-invasive imaging metrics to optimize early treatment switching decisions and prognostic modeling of long-term outcomes

NIH-funded research University of California, San Francisco · NIH-11125945

This research helps doctors use imaging and other tests to choose the best breast cancer treatment for each patient.

Quick facts

Grant typeP01 program project
Study typeNIH-funded research
Funding institutionUniversity of California, San Francisco NIH-funded
Lab location1 site (San Francisco, United States)
Project IDNIH-11125945 on NIH RePORTER

What this research studies

We are working to make sure every breast cancer patient has the best chance of a complete response to treatment. This involves using advanced imaging, tissue analysis, and biological markers to guide treatment decisions. Specifically, we are improving how MRI scans measure tumor changes to help doctors decide if a patient's treatment should be adjusted early on. This work builds on the I-SPY2.2 clinical trial design, aiming to personalize care.

Who could benefit from this research

Good fit: Patients with breast cancer who are undergoing treatment and receiving MRI scans would be ideal candidates for this type of guided care.

Not a fit: Patients whose breast cancer treatment does not involve imaging or those not participating in trials like I-SPY2.2 may not directly benefit from this specific approach.

Why it matters

Potential benefit: If successful, this work could lead to more personalized and effective breast cancer treatments, potentially improving long-term outcomes for patients.

How similar studies have performed: This work builds upon findings from previous I-SPY2 trials and retrospective studies, which have informed refinements to MRI protocols.

Where this research is happening

San Francisco, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Breast CancerBreast Cancer TreatmentCancer Burden
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.