Improving breast cancer surgery outcomes with advanced imaging technology
Official title: Intraoperative quantitative CT imaging of breast specimen for reducing re-surgery rate and tumor cataloguing
Funded at University of Chicago · NIH-10976552 · Data updated 2026-11-12
This study is testing a new imaging technology that helps doctors get clearer 3D pictures of breast tissue during surgery, making it easier to ensure all cancer is removed, which could mean fewer follow-up surgeries for patients.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Chicago NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project start | July 1, 2024 |
| Project end | June 30, 2029 |
| Funding year | 2024 |
| Award (this year) | $673,366 |
| NIH project number | 1R01CA287302-01A1 |
| Project ID | NIH-10976552 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are women undergoing breast-conserving surgery for breast cancer.
✕Less likely to help
Patients who have already undergone mastectomy or those not diagnosed with breast cancer may not benefit from this research.
What this research studies
This research focuses on developing a new imaging technology called dual-energy cone-beam microCT (DECB µCT) specifically for use during breast-conserving surgery. By providing detailed 3D images of lumpectomy specimens, the technology aims to enhance the identification of positive margins, which are critical for ensuring all cancerous tissue is removed. The innovative imaging approach uses advanced algorithms to improve the contrast between breast cancer and surrounding tissues, potentially reducing the need for additional surgeries. Patients undergoing breast-conserving surgery may benefit from this technology, as it could lead to more accurate surgeries and fewer re-operations.
Why it matters
Potential benefit: If successful, this research could significantly reduce the rate of re-surgery for breast cancer patients, improving their overall treatment experience.
How similar studies have gone: Previous research has shown promise in using advanced imaging techniques to improve surgical outcomes, suggesting that this approach could be effective.
Where this research is happening
-
University of Chicago
Chicago, United States Active
Researchers
- Principal investigator: Pan, Xiaochuan — University of Chicago
- Study coordinator: Pan, Xiaochuan
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.