Improving breast cancer screening with advanced imaging technology
Next-Generation Tomosynthesis Pilot Study
This study is testing a new type of breast cancer screening that uses a special 'T' shaped scan to get clearer images and help reduce the number of unnecessary follow-up procedures, and it's looking for women who need diagnostic imaging or a biopsy to join in.
Quick facts
| Grant type | R37 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pennsylvania NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-10919196 on NIH RePORTER |
What this research studies
This research focuses on enhancing breast cancer screening through a next-generation tomosynthesis system that scans in a unique 'T' shape. By addressing limitations of current digital breast tomosynthesis systems, which often lead to poor specificity and high callback rates, this study aims to improve image quality and reduce unnecessary biopsies. Volunteers, particularly women referred for diagnostic imaging or biopsy, will participate in the pilot study, where their imaging results will be analyzed using both conventional and new scanning methods. The study is designed to ensure safety by limiting radiation exposure to a single view.
Who could benefit from this research
Good fit: Ideal candidates for this research are women who have been referred for diagnostic imaging or biopsy due to potential breast abnormalities.
Not a fit: Patients who do not require breast imaging or those with no history of breast abnormalities may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate breast cancer screenings, reducing unnecessary procedures and improving early detection rates.
How similar studies have performed: Previous research has shown promise in improving imaging techniques for breast cancer detection, making this approach a potentially significant advancement in the field.
Where this research is happening
Philadelphia, United States
- University of Pennsylvania — Philadelphia, United States (Active)
Researchers
- Principal investigator: Acciavatti, Raymond Joseph — University of Pennsylvania
- Study coordinator: Acciavatti, Raymond Joseph
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.