Improving breast cancer risk prediction using deep learning from mammograms

Advancing breast cancer risk prediction in national cohorts: the role of mammogram-based deep learning

['FUNDING_U01'] · COLUMBIA UNIVERSITY HEALTH SCIENCES · NIH-10932957

This study is working to improve how we predict breast cancer risk by using advanced computer technology on mammogram images, especially to help Black women, and it aims to create better prevention strategies by combining this information with genetic data from diverse groups of people.

Quick facts

Phase['FUNDING_U01']
Study typeNih_funding
SexAll
SponsorCOLUMBIA UNIVERSITY HEALTH SCIENCES (nih funded)
Locations1 site (NEW YORK, UNITED STATES)
Trial IDNIH-10932957 on ClinicalTrials.gov

What this research studies

This research aims to enhance breast cancer risk prediction by utilizing advanced deep learning techniques applied to mammographic images. It addresses the limitations of existing models, which have shown lower accuracy, particularly in Black women. By validating these deep learning models in real-world settings and combining them with genetic data, the research seeks to create more equitable and effective breast cancer prevention strategies. The study will leverage data from two national cohorts to ensure diverse representation and robust findings.

Who could benefit from this research

Good fit: Ideal candidates for this research include women undergoing routine mammograms, especially those from diverse racial backgrounds, including Black women.

Not a fit: Patients who do not undergo mammograms or those with a history of breast cancer may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more accurate breast cancer risk assessments, particularly for underrepresented populations, ultimately improving prevention and early detection.

How similar studies have performed: Previous research has shown promise in using deep learning for medical imaging, indicating potential success for this novel approach in breast cancer risk prediction.

Where this research is happening

NEW YORK, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Breast Cancer, Breast Cancer Detection, Breast Cancer Gail Model, Breast Cancer Gail Model Risk Assessment Tool, Breast Cancer Prevention

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.