Improving breast cancer imaging and radiation therapy technologies using patient-derived phantoms

SBIR TOPIC 401 PHASE II:

NIH-funded research Malcova INC · NIH-10923637

This study is working on creating lifelike models of breasts using real patient scans to help improve breast cancer imaging and radiation therapy, making it safer and quicker to test new treatments without needing patients to be involved right away.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionMalcova INC NIH-funded
Lab location1 site (Newark, United States)
Project IDNIH-10923637 on NIH RePORTER

What this research studies

This research focuses on enhancing breast cancer imaging and radiation therapy by developing realistic patient-derived phantoms that can be used in clinical trials. By utilizing a large dataset of three-dimensional breast CT images, the project aims to create anthropomorphic phantoms that accurately represent human anatomy, which can help in testing new imaging technologies and radiation treatments. This approach reduces the need for patient involvement in early testing phases, making the process faster and safer. Additionally, the technology may be adapted for imaging applications related to prostate, brain, and lung cancers.

Who could benefit from this research

Good fit: Ideal candidates for benefiting from this research include individuals diagnosed with breast cancer who may require advanced imaging or radiation therapy.

Not a fit: Patients with conditions unrelated to breast, prostate, brain, or lung cancers may not receive direct benefits from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective and safer imaging and radiation therapy options for breast cancer patients.

How similar studies have performed: Other research has shown promise in using patient-derived models for improving imaging technologies, indicating a potential for success in this novel approach.

Where this research is happening

Newark, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Breast Cancer
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.