Improving breast cancer detection and treatment monitoring using advanced ultrasound techniques

Using Label-free Ultrasound Angio-Morphometry Analysis for Improving Ultrasound Specificity in Breast Cancer Detection and Treatment Monitoring

NIH-funded research Mayo Clinic Rochester · NIH-10652455

This study is testing a new, less invasive ultrasound method to help doctors better detect and monitor breast cancer, making it easier for patients to get accurate information without needing costly contrast agents or unnecessary biopsies.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionMayo Clinic Rochester NIH-funded
Lab location1 site (Rochester, United States)
Project IDNIH-10652455 on NIH RePORTER

What this research studies

This research focuses on enhancing the accuracy of breast cancer detection and monitoring by developing a new imaging technique called Label-free Ultrasound Angio-Morphometry Analysis (LUAMA). This method aims to provide detailed information about the microvascular structure of breast masses without the need for contrast agents, which can be invasive and costly. By using high frame rate ultrasound imaging, the study seeks to reduce unnecessary biopsies and improve the assessment of treatment responses. Patients will benefit from a less invasive and more accurate diagnostic tool that could lead to better treatment decisions.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals with suspicious breast masses who are being considered for biopsy.

Not a fit: Patients who have already been diagnosed with breast cancer and are not undergoing preoperative evaluation may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly reduce the number of unnecessary breast biopsies and improve the accuracy of breast cancer monitoring.

How similar studies have performed: Previous research has shown promise in using advanced imaging techniques for cancer detection, suggesting that this approach could lead to meaningful advancements in breast cancer diagnostics.

Where this research is happening

Rochester, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Breast Cancer
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.