Improving breast biopsy accuracy using advanced imaging techniques
Improving diagnostic US for reduction of benign breast biopsies using US-guided Optical Tomography
This study is testing a new imaging method that combines ultrasound with a technique called diffuse optical tomography to help doctors better tell the difference between harmless and harmful breast lumps, which could mean fewer unnecessary biopsies for patients.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Washington University NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project ID | NIH-10541110 on NIH RePORTER |
What this research studies
This research investigates a new imaging technique called ultrasound-guided diffuse optical tomography (DOT) to improve the accuracy of breast biopsies. By combining this advanced imaging with traditional ultrasound, the study aims to better differentiate between benign and malignant breast lesions, potentially reducing the number of unnecessary biopsies. The approach involves analyzing hemoglobin levels and vascularity in breast lesions to inform biopsy decisions. If successful, this method could lead to fewer invasive procedures for patients with low-risk lesions.
Who could benefit from this research
Good fit: Ideal candidates for this research are women with low to moderate risk breast lesions who are being considered for biopsy.
Not a fit: Patients with high-risk breast lesions or those already diagnosed with breast cancer may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly reduce the number of unnecessary breast biopsies for patients, leading to less physical and emotional stress.
How similar studies have performed: Previous research has shown promise in using advanced imaging techniques to improve diagnostic accuracy in breast lesions, suggesting potential for success in this approach.
Where this research is happening
Saint Louis, United States
- Washington University — Saint Louis, United States (Active)
Researchers
- Principal investigator: Zhu, Quing — Washington University
- Study coordinator: Zhu, Quing
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.