Improving brain stimulation techniques for mental health treatment
Validation of Closed-Loop Prefrontal Transcranial Magnetic Stimulation in a Non-Human Primate Model
This study is exploring a new way to use brain stimulation that adjusts to how your brain is working in real-time, with the hope of making treatments more effective for people with mental health issues.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Minnesota NIH-funded |
| Lab location | 1 site (Minneapolis, United States) |
| Project ID | NIH-11049279 on NIH RePORTER |
What this research studies
This research investigates a new method of transcranial magnetic stimulation (TMS) that adapts to individual brain activity in real-time. By using electroencephalographic (EEG) recordings, the study aims to optimize the timing and effectiveness of TMS applied to the prefrontal cortex, which is crucial for mental health. The research will be conducted in non-human primates to gather precise data on brain responses, which will help inform future applications in humans. The goal is to enhance TMS outcomes for patients with psychiatric disorders by identifying the best stimulation parameters and understanding how TMS affects brain plasticity.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals suffering from psychiatric disorders who may benefit from advanced brain stimulation therapies.
Not a fit: Patients with conditions that do not respond to TMS or those who are not eligible for brain stimulation therapies may not receive benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for mental health disorders through personalized brain stimulation techniques.
How similar studies have performed: While closed-loop TMS is a novel approach, preliminary studies in related fields have shown promise in enhancing the effectiveness of brain stimulation techniques.
Where this research is happening
Minneapolis, United States
- University of Minnesota — Minneapolis, United States (Active)
Researchers
- Principal investigator: Opitz, Alexander — University of Minnesota
- Study coordinator: Opitz, Alexander
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.