Improving Brain Signal Analysis for Alzheimer's and Related Dementias
Advanced signal processing methods for neural data analysis to support development of brain dynamic biomarkers for research and clinical applications in patients with Alzheimer's and related dementias
This project aims to create better ways to analyze brain signals from EEG tests to help predict and track Alzheimer's disease and related dementias earlier.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project ID | NIH-11089582 on NIH RePORTER |
What this research studies
We are working on new ways to understand brain activity using EEG, a non-invasive test that measures electrical signals in your brain. Current methods for analyzing these signals aren't always precise enough to track Alzheimer's disease in individuals. Our goal is to develop advanced computer programs that can more accurately detect subtle changes in brain function, even before memory problems become obvious. This could lead to new "digital biomarkers" that help doctors identify Alzheimer's earlier and monitor its progression more effectively.
Who could benefit from this research
Good fit: This research is focused on developing tools for patients with Alzheimer's disease and related dementias, particularly those in early stages or at risk.
Not a fit: Patients who do not have or are not at risk for Alzheimer's disease or related dementias would not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this work could provide new tools for earlier detection and more precise tracking of Alzheimer's disease and related dementias, potentially allowing for earlier interventions.
How similar studies have performed: While EEG features are known to correlate with AD progression, this project focuses on novel, advanced signal processing algorithms to improve individual-level precision, which is a less explored area.
Where this research is happening
Stanford, United States
- Stanford University — Stanford, United States (Active)
Researchers
- Principal investigator: Purdon, Patrick L. — Stanford University
- Study coordinator: Purdon, Patrick L.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.