Improving brain recovery after injury using targeted stimulation
Engineering neuroplasticity using volitional control of activity-dependent optogenetic stimulation in macaque sensorimotor cortex
This work explores how precise brain stimulation can help the brain reorganize and recover function after an injury like a stroke.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Washington NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project ID | NIH-11121071 on NIH RePORTER |
What this research studies
Our brains have an amazing ability to adapt and heal, a process called plasticity, which is especially important after an injury. This project uses advanced tools to gently guide brain activity in specific areas, aiming to strengthen existing connections and even create new ones. We want to see if this targeted approach can help the brain recover lost functions and improve movement after damage. The ultimate goal is to develop new ways to help people regain abilities after conditions like a stroke.
Who could benefit from this research
Good fit: Patients who have experienced brain injuries, such as a stroke, and are seeking ways to improve their recovery and regain lost function may find this research relevant.
Not a fit: Patients without brain injuries or those whose conditions are not related to brain plasticity and recovery may not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this research could lead to new brain stimulation therapies that help patients recover more effectively from conditions like stroke.
How similar studies have performed: While the concept of leveraging brain plasticity for recovery is recognized, this project uses novel engineering tools for precise, activity-dependent stimulation, making its specific approach innovative.
Where this research is happening
Seattle, United States
- University of Washington — Seattle, United States (Active)
Researchers
- Principal investigator: Yazdan Shahmorad, Azadeh — University of Washington
- Study coordinator: Yazdan Shahmorad, Azadeh
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.