Improving brain recovery after cardiac arrest using specialized stem cells
Brain Recovery after Cardiac Arrest with Metabolic Glycoengineered Stem Cells
This study is exploring a new way to help the brain heal after a cardiac arrest by using specially modified stem cells, which could improve recovery for patients who have gone through this experience.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Maryland Baltimore NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-10434716 on NIH RePORTER |
What this research studies
This research focuses on enhancing recovery of the brain following cardiac arrest by utilizing metabolic glycoengineered stem cells. The study aims to improve the viability and integration of these stem cells at the injury site, which is crucial for effective treatment. By modifying the surface properties of the stem cells, the researchers hope to promote better adhesion and differentiation into the necessary cell types that can repair damaged neurons. Patients who have experienced cardiac arrest may benefit from this innovative approach to stem cell therapy.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults aged 21 and older who have survived a cardiac arrest and are experiencing brain injury.
Not a fit: Patients who have not experienced cardiac arrest or those with other unrelated neurological conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved recovery outcomes for patients who have suffered brain injuries due to cardiac arrest.
How similar studies have performed: While stem cell therapy has shown promise in other contexts, the specific application of metabolic glycoengineering in this area is novel and has not been extensively tested.
Where this research is happening
Baltimore, United States
- University of Maryland Baltimore — Baltimore, United States (Active)
Researchers
- Principal investigator: Jia, Xiaofeng — University of Maryland Baltimore
- Study coordinator: Jia, Xiaofeng
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.