NIH-funded research Sbir 2 grant

Improving brain MRI imaging for infants

Official title: Motion-robust brain MRI for infants

Funded at Turing Medical Technologies INC · NIH-10684950 · Data updated 2026-11-12

This study is working on a new software that helps get clearer brain scans for babies by reducing the blurriness caused by their movements, so they can have safe and accurate MRIs without needing anesthesia.

Quick facts

Grant typeSbir 2 grant
Study typeNIH-funded research
Funding institutionTuring Medical Technologies INC
NIH-funded
Lab location1 site (Saint Louis, United States)
Project startJuly 3, 2020
Project endAugust 31, 2025
Funding year2023
Award (this year)$1,775,407
NIH project number5R44MH124567-04
Project IDNIH-10684950 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are infants undergoing brain MRI scans, particularly those at risk for brain injuries or developmental issues.

Less likely to help

Patients who are older than infants or those who do not require MRI imaging will likely not benefit from this research.

What this research studies

This research aims to develop a software solution that minimizes the impact of head motion during brain MRI scans in infants. By addressing the common issue of motion distortion, which affects about 20% of brain MRIs, the project seeks to enhance the quality of imaging without the need for anesthesia, which poses risks to young patients. The approach involves creating infant-compatible motion-sensing and correcting sequences to ensure clearer and more accurate brain images. This innovative method could significantly improve the diagnostic process for infants requiring brain imaging.

Why it matters

Potential benefit: If successful, this research could lead to safer and more effective brain imaging for infants, reducing the need for anesthesia and improving diagnostic accuracy.

How similar studies have gone: While the approach of using software to correct motion in MRI scans is innovative, similar technologies have shown promise in adult populations, indicating potential for success in infants.

Where this research is happening

  • Turing Medical Technologies INC
    Saint Louis, United States
    Active

Researchers

  • Principal investigator: Bertolero, Maxwell — Turing Medical Technologies INC
  • Study coordinator: Bertolero, Maxwell

Related research

Other NIH-funded projects on the same topics.

  • Real-time head motion monitoring for all MRI scans in older adults at risk for Alzheimer’s disease

    A new technology helps reduce patient movement during MRI scans, especially for people 65 and older who are being pre-screened for Alzheimer’s therapies.

    NIH research Turing Medical Technologies INC · Saint Louis, United States · NIH-11536530

  • Commercially ready motion-friendly pediatric brain MRI tool with FIRMM integration

    A patient-friendly technology is being developed to reduce motion-related MRI problems in children by teaming up with a major scanner maker to bring real-time motion monitoring into routine pediatric scans.

    NIH research Turing Medical Technologies INC · Saint Louis, United States · NIH-11330466

  • Using games and feedback to improve brain scans in children before surgery

    This study is testing a fun and interactive way to help kids stay still during brain scans for epilepsy treatment, making the process easier and more accurate so doctors can plan the best care for them.

    NIH research Turing Medical Technologies INC · Saint Louis, United States · NIH-11117053

  • Improving brain MRI for children by reducing motion-related issues

    This study is working on a new software that helps make brain scans for kids clearer and more accurate by reducing blurriness caused by movement, so that doctors can better understand what's going on in their brains.

    NIH research Turing Medical Technologies INC · Saint Louis, United States · NIH-11074617

  • Software to reduce motion-related errors in MRI scans

    This study is working on new software that helps make MRI scans clearer by reducing blurriness caused by patient movement, so that doctors can get better and more accurate images for diagnosing health issues.

    NIH research Turing Medical Technologies INC · Saint Louis, United States · NIH-11047750

  • Using biofeedback to help patients stay still during MRI scans

    This study is testing a new technology that helps patients, especially kids and older adults, stay still during brain MRI scans by giving them real-time feedback, which can lead to clearer images and fewer repeat scans.

    NIH research Turing Medical Technologies INC · Saint Louis, United States · NIH-10756169

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.