NIH-funded research Sbir 2 grant

Improving brain MRI images using advanced software

Official title: Automated enhancement and correction of brain MRI images that leverages the entire imaging exam

Funded at Subtle Medical, INC. · NIH-10951007 · Data updated 2026-11-12

This study is creating a helpful software tool that makes brain MRI images clearer and more complete, so patients can get more accurate results and better treatment options.

Quick facts

Grant typeSbir 2 grant
Study typeNIH-funded research
Funding institutionSubtle Medical, INC.
NIH-funded
Lab location1 site (Menlo Park, United States)
Project startSeptember 5, 2023
Project endAugust 31, 2026
Funding year2024
Award (this year)$1,135,581
NIH project number4R44MH135725-02
Project IDNIH-10951007 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals undergoing brain MRI scans who may benefit from enhanced imaging quality.

Less likely to help

Patients who have already received brain MRI scans that are not subject to enhancement or correction may not benefit from this research.

What this research studies

This research aims to develop a software tool that enhances brain MRI images by correcting errors and filling in missing data. Using advanced machine learning techniques, the software will integrate into existing radiology workflows to identify and rectify issues such as motion artifacts and incomplete scans. By ensuring that all necessary MRI acquisitions are complete and of high quality, this tool seeks to improve the overall diagnostic process for brain imaging. Patients can expect that their MRI results will be more accurate and reliable, leading to better-informed treatment decisions.

Why it matters

Potential benefit: If successful, this research could lead to more accurate brain MRI results, improving patient care and treatment outcomes.

How similar studies have gone: Other research has shown success in using machine learning for image enhancement, indicating a promising approach in this area.

Where this research is happening

  • Subtle Medical, INC.
    Menlo Park, United States
    Active

Researchers

  • Principal investigator: Zhou, Zechen — Subtle Medical, INC.
  • Study coordinator: Zhou, Zechen

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.