Improving brain injury detection in critically-ill children using advanced imaging techniques
Optical Functional Neuroimaging of Acute and Chronic Hypoxia
This study is working on new ways to use light to see brain injuries in seriously ill kids, helping doctors find problems faster and improve care for children who have had issues like heart defects or were born too early.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Children's Hosp of Philadelphia NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-10862811 on NIH RePORTER |
What this research studies
This research focuses on developing optical neuroimaging techniques to enhance the detection of neurological injuries in critically-ill children. The approach involves training in mouse models of hypoxia and advanced statistical methods to analyze brain activity. By utilizing these methods, the research aims to identify reliable imaging biomarkers that can be used at the bedside to minimize hypoxic injury. This could lead to better outcomes for children who have experienced brain injuries due to conditions like congenital heart disease or extreme prematurity.
Who could benefit from this research
Good fit: Ideal candidates for this research are critically-ill children who are at risk of neurological injuries due to conditions such as congenital heart disease or extreme prematurity.
Not a fit: Patients who are not critically-ill or those outside the pediatric age range may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved detection and intervention strategies for neurological injuries in critically-ill children.
How similar studies have performed: Other research has shown promise in using advanced imaging techniques for neurological assessments, indicating potential success for this approach.
Where this research is happening
Philadelphia, United States
- Children's Hosp of Philadelphia — Philadelphia, United States (Active)
Researchers
- Principal investigator: White, Brian Richard — Children's Hosp of Philadelphia
- Study coordinator: White, Brian Richard
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.