Improving brain imaging with advanced SPECT technology

High-performance SPECT for dynamic brain imaging

['FUNDING_R01'] · MASSACHUSETTS GENERAL HOSPITAL · NIH-10912817

This study is working on a new, portable brain scanner that takes clear pictures of the brain to help doctors better diagnose and track conditions like Alzheimer's disease, all while keeping radiation exposure low for patients.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorMASSACHUSETTS GENERAL HOSPITAL (nih funded)
Locations1 site (BOSTON, UNITED STATES)
Trial IDNIH-10912817 on ClinicalTrials.gov

What this research studies

This research focuses on developing a new portable Single Photon Emission Computed Tomography (SPECT) scanner specifically designed for dynamic brain imaging. The goal is to achieve high resolution and sensitivity in brain imaging, which is crucial for diagnosing and monitoring conditions like Alzheimer's disease and other forms of dementia. By utilizing innovative detector technology, the project aims to create a scanner that can provide clearer images while using lower radiation doses, making it safer for patients. This advancement could facilitate more effective longitudinal studies and better patient management.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals diagnosed with Alzheimer's disease or other forms of dementia who require brain imaging for diagnosis or treatment monitoring.

Not a fit: Patients with conditions unrelated to brain imaging or those who do not require imaging for their diagnosis may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more accurate and safer brain imaging techniques for diagnosing and monitoring Alzheimer's disease and other neurological conditions.

How similar studies have performed: Other research has shown promise in improving imaging technologies, but this specific approach using portable SPECT for dynamic brain imaging is relatively novel.

Where this research is happening

BOSTON, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Alzheimer disease dementia, Alzheimer syndrome, Alzheimer's Disease

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.