Improving brain imaging to understand brain function better

Advanced functional MRI of cerebral cortical layers in the human brain using ultrahigh-resolution linescan MRI technology

['FUNDING_FELLOWSHIP'] · MASSACHUSETTS GENERAL HOSPITAL · NIH-11067202

This study is testing a new way to take pictures of the brain that helps us see how different layers of the brain work together, which could lead to better tools for diagnosing and treating brain conditions.

Quick facts

Phase['FUNDING_FELLOWSHIP']
Study typeNih_funding
SexAll
SponsorMASSACHUSETTS GENERAL HOSPITAL (nih funded)
Locations1 site (BOSTON, UNITED STATES)
Trial IDNIH-11067202 on ClinicalTrials.gov

What this research studies

This research focuses on enhancing functional MRI (fMRI) technology to measure brain activity more accurately by examining individual layers of the cerebral cortex. By using a novel linescan fMRI method, the researchers aim to achieve higher spatial resolution, allowing for a better understanding of how different brain layers contribute to overall brain function. This approach will involve advanced imaging techniques and comparisons with traditional methods to validate its effectiveness. Patients may benefit from improved diagnostic tools and treatment strategies based on a deeper understanding of brain circuitry.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals with neurological disorders or those undergoing evaluation for cognitive impairments.

Not a fit: Patients with stable neurological conditions who do not require advanced imaging or those who are not undergoing cognitive assessments may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more precise brain imaging techniques that enhance our understanding of brain function and improve treatment options for neurological conditions.

How similar studies have performed: While linescan fMRI is a novel approach in human neuroscience, similar techniques have shown promise in animal studies, indicating potential for success in human applications.

Where this research is happening

BOSTON, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.