Improving brain imaging to monitor ion pump dysfunction

Anatomically Guided Sodium MRI: Accurately Monitoring Chronic Ion Pump Dysfunction in the Human Brain

NIH-funded research Stanford University · NIH-11082435

This study is working on a new way to take clearer pictures of the brain to help doctors better understand and track problems with brain function related to ion pumps, which could lead to more accurate diagnoses for patients.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionStanford University NIH-funded
Lab location1 site (Stanford, United States)
Project IDNIH-11082435 on NIH RePORTER

What this research studies

This research focuses on developing a new method for creating high-resolution sodium images of the brain, which can help monitor chronic ion pump dysfunction. By using advanced techniques in Bayesian image reconstruction and manifold mapping, the study aims to enhance the clarity and detail of brain scans. This approach allows for better utilization of anatomical information from high-resolution scans to improve the quality of lower-resolution images, making it easier to detect subtle changes in brain function. Patients may benefit from more accurate diagnoses and monitoring of brain conditions related to ion pump dysfunction.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals experiencing chronic brain conditions that may involve ion pump dysfunction.

Not a fit: Patients with acute brain injuries or conditions unrelated to ion pump dysfunction may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more precise monitoring and diagnosis of brain conditions, improving patient outcomes.

How similar studies have performed: Previous research has shown promise in using advanced imaging techniques for brain monitoring, suggesting potential success for this novel approach.

Where this research is happening

Stanford, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.