Improving brain imaging techniques for neurological disorders
Segmenting Brain Structures for Neurological Disorders
This study is working on improving MRI technology to help doctors better see and understand changes in the brains of people with conditions like Alzheimer's and Parkinson's, making it easier to diagnose and track treatment progress.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10527314 on NIH RePORTER |
What this research studies
This research focuses on enhancing Magnetic Resonance Imaging (MRI) technology to better understand and quantify changes in brain structures affected by neurological disorders like Alzheimer's and Parkinson's disease. By developing open-source tools that can automatically segment various brain structures, the project aims to improve the accuracy of diagnosing and assessing the effectiveness of treatments. The research involves collecting datasets for manual labeling, creating comprehensive documentation, and ensuring the tools are user-friendly for clinicians and researchers. Ultimately, this work seeks to provide valuable resources to over 32,000 researchers in the field.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with Alzheimer's disease or other neurological disorders.
Not a fit: Patients with neurological conditions not related to Alzheimer's or Parkinson's disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate diagnoses and better treatment assessments for patients with neurological disorders.
How similar studies have performed: Previous research has shown success in using MRI technology for brain structure analysis, making this approach a promising extension of established methods.
Where this research is happening
Boston, United States
- Massachusetts General Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Fischl, Bruce — Massachusetts General Hospital
- Study coordinator: Fischl, Bruce
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.