Improving brain imaging quality for Alzheimer's disease diagnosis
Official title: Automated Quality Evaluation and Harmonization for Multisite ASL MRI Data
Funded at University of Pennsylvania · NIH-10912038 · Data updated 2026-11-12
This study is working on improving brain scans for diagnosing Alzheimer's and similar conditions, so that patients can get more accurate results and better tracking of their health over time.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pennsylvania NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project start | September 1, 2023 |
| Project end | August 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $207,955 |
| NIH project number | 5R21AG080518-02 |
| Project ID | NIH-10912038 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals diagnosed with Alzheimer's disease or related dementias who are undergoing brain imaging.
✕Less likely to help
Patients with other neurological conditions unrelated to Alzheimer's disease may not receive benefit from this research.
What this research studies
This research focuses on enhancing the quality of brain imaging data used to diagnose Alzheimer's disease and related dementias. It aims to develop automated methods to evaluate and harmonize imaging data collected from multiple sites, ensuring consistency and accuracy in the assessment of cerebral blood flow. By addressing issues related to variability in imaging protocols and artifacts, the study seeks to improve the reliability of brain scans in clinical settings. Patients may benefit from more accurate diagnoses and better monitoring of disease progression as a result of this work.
Why it matters
Potential benefit: If successful, this research could lead to more accurate and reliable diagnoses of Alzheimer's disease and related dementias.
How similar studies have gone: Previous research has shown promise in improving imaging techniques for Alzheimer's disease, but this specific approach to harmonizing multisite data is relatively novel.
Where this research is happening
-
University of Pennsylvania
Philadelphia, United States Active
Researchers
- Principal investigator: Dolui, Sudipto — University of Pennsylvania
- Study coordinator: Dolui, Sudipto
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.