Improving brain imaging for better understanding of Alzheimer's disease
Multi-Site Neuroimage Harmonization for Personalized Brain Disorder Analysis
['FUNDING_R01'] · UNIV OF NORTH CAROLINA CHAPEL HILL · NIH-11212120
This study is working on improving how we look at brain scans to better understand and predict how Alzheimer's disease and similar conditions progress, so we can help people with early signs of memory problems get the right support sooner.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIV OF NORTH CAROLINA CHAPEL HILL (nih funded) |
| Locations | 1 site (CHAPEL HILL, UNITED STATES) |
| Trial ID | NIH-11212120 on ClinicalTrials.gov |
What this research studies
This research focuses on enhancing the analysis of brain images to better predict the progression of Alzheimer's disease and related disorders. By using advanced machine learning techniques, the project aims to harmonize neuroimaging data collected from multiple sites, which can vary due to different equipment and protocols. The goal is to create tools that allow for more accurate interpretation of brain images, ultimately aiding in the development of timely interventions for patients experiencing early cognitive decline. The study will analyze data from over 5,300 subjects to ensure robust findings.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals experiencing subjective cognitive decline or those at risk for Alzheimer's disease.
Not a fit: Patients with advanced Alzheimer's disease or those not experiencing any cognitive decline may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate predictions of Alzheimer's disease progression, allowing for earlier and more personalized treatment options.
How similar studies have performed: Previous research has shown promise in using machine learning for neuroimaging analysis, indicating that this approach could yield significant advancements in understanding Alzheimer's disease.
Where this research is happening
CHAPEL HILL, UNITED STATES
- UNIV OF NORTH CAROLINA CHAPEL HILL — CHAPEL HILL, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LIU, MINGXIA — UNIV OF NORTH CAROLINA CHAPEL HILL
- Study coordinator: LIU, MINGXIA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Alzheimer disease dementia, Alzheimer syndrome, Alzheimer's Disease, Alzheimer's disease and related dementia