Improving brain health in people with HIV who drink heavily
Cognitive and Inflammation Targeted Gut-Brain Interventions in People Living with HIV who are High-Risk Alcohol Users
['FUNDING_P01'] · UNIVERSITY OF FLORIDA · NIH-10910904
This study is looking at how two gentle treatments, one that stimulates a nerve in your neck and another that adds good bacteria to your gut, can help improve thinking skills and reduce inflammation in people with HIV who also drink a lot of alcohol. If you join, you'll see if these treatments can boost your brain health and overall well-being!
Quick facts
| Phase | ['FUNDING_P01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF FLORIDA (nih funded) |
| Locations | 1 site (GAINESVILLE, UNITED STATES) |
| Trial ID | NIH-10910904 on ClinicalTrials.gov |
What this research studies
This research investigates the effects of two non-invasive interventions, transcutaneous vagal nerve stimulation (tVNS) and probiotic supplementation, on cognitive function and inflammation in individuals living with HIV who are high-risk alcohol users. The study aims to enhance brain health and gut microbiome balance while exploring the gut-brain connection. Participants will undergo these interventions to assess improvements in cognitive abilities and overall health outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals living with HIV who are also high-risk alcohol users.
Not a fit: Patients who do not have HIV or do not engage in high-risk alcohol use may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved cognitive function and quality of life for patients living with HIV who struggle with alcohol use.
How similar studies have performed: Previous research has shown promise in using non-invasive interventions like tVNS for cognitive improvement, suggesting potential success for this approach.
Where this research is happening
GAINESVILLE, UNITED STATES
- UNIVERSITY OF FLORIDA — GAINESVILLE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: PORGES, ERIC — UNIVERSITY OF FLORIDA
- Study coordinator: PORGES, ERIC
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Acquired Immune Deficiency Syndrome Virus, Acquired Immunodeficiency Syndrome Virus