Improving brain health in children who survived brain tumors treated with radiation
Image-guided combination therapies for radiotherapy-induced neurocognitive impairment in pediatric brain tumor survivors
This study is looking for new ways to help children who have survived brain tumors and had radiation treatment, by using special cells and advanced technology to protect their brains and improve their quality of life.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-10854903 on NIH RePORTER |
What this research studies
This research focuses on addressing the neurocognitive decline and brain injuries that affect children who have survived central nervous system tumors and received radiotherapy. It explores innovative strategies to protect the brain from damage caused by radiation, including the use of regenerative stem cells and advanced drug delivery systems. By employing nanotechnology and imaging techniques, the study aims to enhance the effectiveness of treatments and monitor their impact on brain health. The goal is to develop therapies that can improve the quality of life for these young survivors.
Who could benefit from this research
Good fit: Ideal candidates for this research are pediatric patients who have survived central nervous system tumors and have undergone radiotherapy.
Not a fit: Patients who have not received radiotherapy or do not have a history of central nervous system tumors may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that significantly improve cognitive function and overall quality of life for pediatric brain tumor survivors.
How similar studies have performed: Previous research has shown promise in using similar neuroprotective strategies and advanced imaging techniques for brain injury recovery, indicating potential for success in this area.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Ngen, Ethel Joso — Johns Hopkins University
- Study coordinator: Ngen, Ethel Joso
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.