Improving brain connectivity measurements in children with autism
Statistical approaches to improving functional connectivity estimates with an application to autism
['FUNDING_R01'] · EMORY UNIVERSITY · NIH-11058351
This study is looking to improve how we understand brain connections in children with autism by using special brain scans while they watch a movie, so we can get better results even if they move around a bit.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | EMORY UNIVERSITY (nih funded) |
| Locations | 1 site (ATLANTA, UNITED STATES) |
| Trial ID | NIH-11058351 on ClinicalTrials.gov |
What this research studies
This research focuses on enhancing the accuracy of brain connectivity estimates using functional magnetic resonance imaging (fMRI) in children with autism spectrum disorder (ASD). The team aims to develop new statistical methods that address issues like participant head motion, which can skew results and lead to conflicting findings in the literature. By analyzing data from children during specific tasks, such as watching a movie, the research seeks to provide a clearer understanding of brain connectivity patterns in ASD. This approach may help include a broader range of children on the autism spectrum, particularly those who are often excluded from studies due to high motion.
Who could benefit from this research
Good fit: Ideal candidates for this research are children aged 0-11 years who are diagnosed with autism spectrum disorder.
Not a fit: Patients who do not have autism spectrum disorder or are outside the age range of 0-11 years may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate diagnoses and targeted interventions for children with autism spectrum disorder.
How similar studies have performed: Other research has shown promise in improving brain connectivity assessments using innovative statistical methods, suggesting potential for success in this approach.
Where this research is happening
ATLANTA, UNITED STATES
- EMORY UNIVERSITY — ATLANTA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: RISK, BENJAMIN BREWSTER — EMORY UNIVERSITY
- Study coordinator: RISK, BENJAMIN BREWSTER
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: autism spectral disorder, autism spectrum disorder, Autistic Disorder, autistic spectrum disorder