Improving brain chemical measurement using advanced modeling techniques
Model Selection for Magnetic Resonance Spectroscopy
['FUNDING_R01'] · JOHNS HOPKINS UNIVERSITY · NIH-11144948
This study is looking at a special brain scan that helps doctors see the chemicals in your brain more clearly, which could lead to better ways to diagnose and treat brain conditions.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | JOHNS HOPKINS UNIVERSITY (nih funded) |
| Locations | 1 site (BALTIMORE, UNITED STATES) |
| Trial ID | NIH-11144948 on ClinicalTrials.gov |
What this research studies
This research focuses on enhancing the accuracy of in-vivo proton magnetic resonance spectroscopy (1H-MRS), a non-invasive technique that measures various biochemicals in the human brain. By employing multiple candidate models for data analysis instead of relying on a single model, the study aims to better capture the variability in biochemical measurements. This approach will help in understanding metabolic changes related to neuronal health, cell proliferation, and tumor markers, which are crucial for diagnosing and monitoring treatment responses in brain conditions. Patients may benefit from improved diagnostic accuracy and personalized treatment strategies based on more reliable biochemical data.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with brain tumors or other neurological disorders who require metabolic assessment through advanced imaging techniques.
Not a fit: Patients with conditions unrelated to brain health or those who do not require biochemical monitoring may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate diagnoses and better monitoring of treatment responses for patients with brain tumors and other neurological conditions.
How similar studies have performed: Previous research has shown promise in improving diagnostic techniques through advanced modeling approaches, indicating potential success for this novel methodology.
Where this research is happening
BALTIMORE, UNITED STATES
- JOHNS HOPKINS UNIVERSITY — BALTIMORE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: OELTZSCHNER, GEORG — JOHNS HOPKINS UNIVERSITY
- Study coordinator: OELTZSCHNER, GEORG
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.