Improving brain blood flow measurement using advanced MRI techniques
Academic Industrial Partnership on Advanced Perfusion MRI
This study is working on improving a special type of brain scan that measures blood flow in the brain, which can help doctors better understand and monitor brain health for patients with various conditions.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pennsylvania NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-11116841 on NIH RePORTER |
What this research studies
This research focuses on enhancing arterial spin labeled (ASL) perfusion MRI, a noninvasive imaging technique that quantifies blood flow in the brain. By using magnetic labeling of blood water, this method provides critical insights into cerebral blood flow, which is essential for understanding brain health and function. The project aims to develop and refine ASL MRI technologies for clinical use, ensuring they keep pace with the latest research advancements. Patients may benefit from improved diagnostic capabilities and better monitoring of brain conditions through this innovative imaging approach.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with neurological disorders or conditions affecting brain blood flow, such as stroke, dementia, or brain tumors.
Not a fit: Patients with stable neurological conditions that do not affect blood flow or those who are not undergoing brain imaging may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate assessments of brain blood flow, aiding in the diagnosis and treatment of various neurological conditions.
How similar studies have performed: Previous research has shown promising results with ASL MRI techniques, indicating a strong potential for success in this area.
Where this research is happening
Philadelphia, United States
- University of Pennsylvania — Philadelphia, United States (Active)
Researchers
- Principal investigator: Detre, John a — University of Pennsylvania
- Study coordinator: Detre, John a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.