Improving brain blood flow assessment for stroke treatment
Arterial input function Independent Measures of Perfusion with Physics Driven Models
This study is looking to improve how doctors check blood flow in the brains of people having a stroke, using advanced MRI techniques to help choose the best patients for a specific treatment that can remove blood clots.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of North Carolina Chapel Hill NIH-funded |
| Lab location | 1 site (Chapel Hill, United States) |
| Project ID | NIH-10688978 on NIH RePORTER |
What this research studies
This research focuses on enhancing the evaluation of brain blood flow in patients experiencing acute ischemic stroke (AIS). By utilizing advanced imaging techniques, particularly magnetic resonance imaging (MRI), the study aims to develop more precise methods for selecting patients who would benefit from mechanical thrombectomy. The approach involves analyzing patient-specific data and optimizing the imaging process to better identify the ischemic penumbra and infarct core. This could lead to improved treatment decisions and outcomes for stroke patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients experiencing acute ischemic stroke who require assessment for potential mechanical thrombectomy.
Not a fit: Patients with non-ischemic strokes or those who are not candidates for mechanical thrombectomy may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate patient selection for stroke interventions, ultimately improving recovery outcomes.
How similar studies have performed: Previous research has shown promise in using advanced imaging techniques for stroke assessment, indicating that this approach could lead to significant advancements in treatment.
Where this research is happening
Chapel Hill, United States
- Univ of North Carolina Chapel Hill — Chapel Hill, United States (Active)
Researchers
- Principal investigator: Lee, Yueh Z — Univ of North Carolina Chapel Hill
- Study coordinator: Lee, Yueh Z
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.