Improving brain blood flow assessment for stroke treatment
Arterial input function Independent Measures of Perfusion with Physics Driven Models
This study is looking at new ways to check blood flow in the brains of people who have had a stroke, using advanced imaging techniques to help doctors choose the best treatments and improve recovery.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of North Carolina Chapel Hill NIH-funded |
| Lab location | 1 site (Chapel Hill, United States) |
| Project ID | NIH-10494211 on NIH RePORTER |
What this research studies
This research investigates new methods for assessing brain blood flow in patients experiencing acute ischemic stroke (AIS). By utilizing advanced imaging techniques, specifically magnetic resonance imaging (MRI) and computer tomography (CT), the study aims to enhance the precision of patient selection for treatments like mechanical thrombectomy. The approach focuses on developing physics-driven models that can provide independent measures of perfusion, which is crucial for determining the extent of brain damage and guiding effective interventions. Patients will be evaluated using these innovative imaging methods to improve treatment outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have recently experienced an acute ischemic stroke and require assessment for treatment options.
Not a fit: Patients who have not experienced a stroke or those with chronic neurological conditions unrelated to acute ischemic stroke may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate and timely treatments for stroke patients, potentially improving recovery and reducing long-term disability.
How similar studies have performed: Previous research has shown promise in using advanced imaging techniques for stroke assessment, indicating that this approach could lead to significant advancements in treatment selection.
Where this research is happening
Chapel Hill, United States
- Univ of North Carolina Chapel Hill — Chapel Hill, United States (Active)
Researchers
- Principal investigator: Lee, Yueh Z — Univ of North Carolina Chapel Hill
- Study coordinator: Lee, Yueh Z
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.