Improving brachytherapy for cervical cancer using MRI technology

Changing brachytherapy with MRI remnant-tumor segmentation and active-catheter placement

['FUNDING_R01'] · JOHNS HOPKINS UNIVERSITY · NIH-10805453

This study is looking at a new way to help people with cervical cancer by using MRI to better find leftover tumors after radiation treatment, so doctors can place tiny tubes more accurately and safely, leading to fewer side effects and better results for patients.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorJOHNS HOPKINS UNIVERSITY (nih funded)
Locations1 site (BALTIMORE, UNITED STATES)
Trial IDNIH-10805453 on ClinicalTrials.gov

What this research studies

This research focuses on enhancing the treatment of cervical cancer by using MRI to accurately identify residual tumors after initial radiation therapy. The approach involves placing catheters into the tumor with the guidance of MRI, which helps avoid damage to surrounding healthy tissues. By improving the precision of catheter placement, the study aims to reduce complications and improve treatment outcomes for patients. The research seeks to streamline the process, making it less labor-intensive and more effective.

Who could benefit from this research

Good fit: Ideal candidates for this research are women diagnosed with locally advanced cervical cancer who are undergoing treatment involving external beam radiation followed by brachytherapy.

Not a fit: Patients with early-stage cervical cancer or those who are not candidates for brachytherapy may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective and safer treatment options for women with cervical cancer.

How similar studies have performed: Previous research has shown that MRI-guided brachytherapy can improve treatment outcomes, indicating that this approach has potential for success.

Where this research is happening

BALTIMORE, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Cancers, neoplasm/cancer

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.