Improving bone marrow aspiration procedures with advanced imaging technology
Official title: Deep-UV Microscopy for Real-Time Adequacy Analysis of Bone Marrow Aspirates
Funded at Cellia Science, INC. · NIH-11069801 · Data updated 2026-11-12
This study is testing a new tool that uses special light to quickly check if bone marrow samples are good enough for testing, making the process faster and easier for patients getting bone marrow aspirations.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cellia Science, INC. NIH-funded |
| Lab location | 1 site (Fayetteville, United States) |
| Project start | June 11, 2025 |
| Project end | April 30, 2027 |
| Funding year | 2025 |
| Award (this year) | $1,074,143 |
| NIH project number | 2R44EB035057-02 |
| Project ID | NIH-11069801 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include patients undergoing bone marrow aspiration procedures, particularly those with aplastic anemia or other hematological conditions.
✕Less likely to help
Patients who are not undergoing bone marrow aspirations or those with conditions unrelated to bone marrow analysis may not benefit from this research.
What this research studies
This research focuses on enhancing the quality and reliability of bone marrow aspiration procedures by developing a new instrument that uses deep-ultraviolet (UV) microscopy for rapid assessment of sample adequacy. The technique allows for real-time imaging of bone marrow samples without the need for staining, making it faster and more efficient than traditional methods. By utilizing machine learning algorithms, the system can automatically evaluate the quality of the aspirate, providing immediate feedback during the procedure. This innovation aims to reduce the time and resources needed for sample analysis while improving diagnostic accuracy.
Why it matters
Potential benefit: If successful, this research could lead to quicker and more accurate assessments of bone marrow samples, improving patient outcomes in conditions like aplastic anemia and various cancers.
How similar studies have gone: Previous research has shown promising results with similar imaging techniques, indicating potential for success in this novel approach.
Where this research is happening
-
Cellia Science, INC.
Fayetteville, United States Active
Researchers
- Principal investigator: Powless, Amy J — Cellia Science, INC.
- Study coordinator: Powless, Amy J
Related research
Other NIH-funded projects on the same topics.
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Deep-UV microscopy to judge bone marrow samples in real time
A fast, bedside imaging tool uses deep-UV light to decide if a bone marrow sample is adequate during the procedure, helping clinicians get enough material on the first try.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.