Improving bone healing in older patients with a new adhesive for fractures
Official title: Commercialization of an Improved Treatment of Extremity Fractures Using a Regenerative Bone Adhesive to Accelerate Bone Healing in Aging Patients
Funded at Revbio, INC. · NIH-10934600 · Data updated 2026-11-12
This study is testing a new glue called Tetranite® that helps older patients heal better from broken bones by filling in gaps and making the bones more stable, so they can recover faster and avoid problems after surgery.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Revbio, INC. NIH-funded |
| Lab location | 1 site (Lowell, UNITED STATES) |
| Project start | September 30, 2023 |
| Project end | August 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $1,240,327 |
| NIH project number | 5SB1AG085803-02 |
| Project ID | NIH-10934600 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are elderly patients who have experienced fragility fractures in their extremities.
✕Less likely to help
Patients who are not elderly or those who have fractures that do not require surgical intervention may not benefit from this research.
What this research studies
This research focuses on developing a novel bone adhesive called Tetranite® that aims to enhance the healing process for extremity fractures in aging patients. The adhesive works by filling gaps in bone and providing stability, which can help prevent complications such as nonunion and hardware failure after surgery. By using Tetranite® alongside traditional fixation methods, the goal is to accelerate recovery and improve overall outcomes for patients who suffer from fragility fractures. The research will involve clinical trials to assess the effectiveness and safety of this new treatment approach.
Why it matters
Potential benefit: If successful, this research could significantly improve the healing process for older patients with fractures, reducing the risk of complications and the need for revision surgeries.
How similar studies have gone: Previous research has shown promise in using similar regenerative approaches for bone healing, indicating potential for success with this novel adhesive.
Where this research is happening
-
Revbio, INC.
Lowell, United States Active
Researchers
- Principal investigator: Hess, Brian — Revbio, INC.
- Study coordinator: Hess, Brian
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.