Improving bone healing in older adults using new therapies
Angiogenic Therapy: Novel Approaches to Enhance Bone Regeneration in Aging
This study is looking at ways to help older adults heal faster from bone fractures by boosting the cells that help create new blood vessels, and it aims to find new treatments that could make recovery easier for those over 65.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Indiana University Indianapolis NIH-funded |
| Lab location | 1 site (Indianapolis, United States) |
| Project ID | NIH-10570206 on NIH RePORTER |
What this research studies
This research investigates how to enhance bone regeneration in older adults, particularly those over 65, who often experience delayed healing after fractures. The study focuses on the role of specific cells involved in blood vessel formation and how they can be stimulated to improve healing. By using a mouse model, researchers will explore the effects of novel agents that promote the function of these cells, potentially leading to faster recovery from fractures. The findings could provide insights into new treatments that help older patients heal more effectively.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults, particularly those aged 65 and above, who have experienced bone fractures.
Not a fit: Patients who are younger than 65 or do not have a history of bone fractures may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved healing outcomes for older adults suffering from fractures.
How similar studies have performed: Previous studies have shown promising results in enhancing bone healing through similar approaches, indicating potential for success in this research.
Where this research is happening
Indianapolis, United States
- Indiana University Indianapolis — Indianapolis, United States (Active)
Researchers
- Principal investigator: Kacena, Melissa a — Indiana University Indianapolis
- Study coordinator: Kacena, Melissa a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.