Improving blood transfusions for patients with septic shock
A Learning Health System Approach to Improve the Effectiveness of Blood Transfusions during Septic Shock
['FUNDING_OTHER'] · BOSTON UNIVERSITY MEDICAL CAMPUS · NIH-10865638
This study is looking at how to make blood transfusions work better for patients with septic shock, especially those who also have anemia, by figuring out if we should only look at hemoglobin levels or if we should consider other health signs too.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | BOSTON UNIVERSITY MEDICAL CAMPUS (nih funded) |
| Locations | 1 site (BOSTON, UNITED STATES) |
| Trial ID | NIH-10865638 on ClinicalTrials.gov |
What this research studies
This research investigates how to enhance the effectiveness of blood transfusions in patients experiencing septic shock, a severe condition often linked to infection. It aims to determine whether blood transfusions should be based solely on hemoglobin levels or if additional clinical criteria should be considered. By utilizing a Learning Health System approach, the study will benchmark current transfusion practices and gather data to inform better treatment guidelines. Patients with septic shock who develop anemia will be the focus of this investigation.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with septic shock who have low hemoglobin levels.
Not a fit: Patients who do not have septic shock or those whose anemia is unrelated to this condition may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective blood transfusion practices, potentially reducing morbidity and mortality in patients with septic shock.
How similar studies have performed: Previous research has indicated that standard transfusion practices may be harmful, suggesting that this approach could lead to significant advancements in treatment.
Where this research is happening
BOSTON, UNITED STATES
- BOSTON UNIVERSITY MEDICAL CAMPUS — BOSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BOSCH, NICHOLAS A — BOSTON UNIVERSITY MEDICAL CAMPUS
- Study coordinator: BOSCH, NICHOLAS A
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Acute Lung Injury, Acute Pulmonary Injury