Improving blood tests for monitoring aortic aneurysms
Official title: Enhanced Biochemical Monitoring for Aortic Aneurysm Disease
Funded at Univ of North Carolina Chapel Hill · NIH-11092861 · Data updated 2026-11-12
This study is working on new blood tests to help people with aortic aneurysms get diagnosed and monitored more easily and affordably, instead of relying on expensive imaging tests.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of North Carolina Chapel Hill NIH-funded |
| Lab location | 1 site (Chapel Hill, United States) |
| Project start | June 1, 2023 |
| Project end | May 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $652,211 |
| NIH project number | 5R01HL169390-03 |
| Project ID | NIH-11092861 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals at risk for aortic aneurysms, such as older adults or those with a family history of the condition.
✕Less likely to help
Patients who do not have aortic aneurysms or are not at risk for developing them may not benefit from this research.
What this research studies
This research aims to develop new blood tests that can help diagnose and monitor aortic aneurysms, a condition that can lead to serious health issues if not detected early. Currently, diagnosing this condition relies heavily on expensive imaging techniques, but this project seeks to create point-of-care biomarker assays that can provide timely information about the disease's progression. By analyzing blood samples from a large biorepository, the researchers will focus on identifying specific biomarkers that indicate the presence and severity of aortic aneurysms. This approach could make monitoring more accessible and less costly for patients.
Why it matters
Potential benefit: If successful, this research could lead to more accessible and cost-effective monitoring of aortic aneurysms, potentially saving lives through earlier detection and intervention.
How similar studies have gone: Previous research has shown promise in using biomarkers for monitoring other cardiovascular conditions, suggesting that this approach may also be effective for aortic aneurysms.
Where this research is happening
-
Univ of North Carolina Chapel Hill
Chapel Hill, United States Active
Researchers
- Principal investigator: Akerman, Adam William — Univ of North Carolina Chapel Hill
- Study coordinator: Akerman, Adam William
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.